An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region the fresh or dried plants are used externally to treat a wide range of skin problems, including. This study focuses on developing two quantitative methods of coixol in s. Plantaginaceae, commonly known as sweet broom, is a herbal medical plant widely used in the indigenous system of medicine. This plant may be known by one or more common names in different places, and some are listed above. Waisundara 3 department of horticulture and landscape gardening, faculty of agriculture and plantation management. Effect of different concentrations of cytokinins bap, 2ip and kin singly in ms medium on shoot multiplication of scoparia dulcis from shoot tips and nodal segments data recorded after 8 weeks of culture and 20 explants were used for each treatment.
Goatweed scoparia dulcis, also referred to as sweet broom and licorice weed, is a perennial plant that is becoming a serious problem in pastures. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. Two new labdane diterpenoids denoted scoparicol a 1 and scoparicol b 2 were isolated from the aerial parts of scoparia dulcis l. It is native to the neotropics but it can be found throughout the tropical and subtropical world. Effect of scoparia dulcis sweet broomweed plant extract on. Department of agriculture agricultural research service. Genetix plasmid dna isolation kit was used to extract plasmid dna from li cells genentix biotech asia pvt lt, new delhi, india. Pdf effect of an aqueous extract of scoparia dulcis on. Scrophulariaceae, collected from paddy fields in kalutara, sri lanka in may 2001, was authenticated by dr. Both compounds were tested for their attenuating effect on palmitateinduced viability at 25 and 50. Nephrotoxicity was induced by a single intraperitoneal administration of cisplatin 6 mgkg in wistar rats. Functional characterization of nadphcytochrome p450. A problematic weed in citrus groves for many years, goatweed now appears to be proliferating in improved pastures as the calls for its identification and control have increased greatly over the past couple of years.
Article processing charges frequently asked questions download ms word 2003 template download ms word 2007 template researchers. Administration of scoparia dulcis 200 mgkgbw extract to diabetic rats for 6 weeks, caused a. In the present study the terpenoids and terpenoid fractions isolated from 1. Visited 363 times, 1 visits today downloads pdf downloads. Phytochemical investigation of the ethanol extract of the whole plant of scoparia dulcis, has resulted in the isolation of 4, 5, 7trihydroxy6methoxyflavone, commonly called hispidulin and a. The pharmacognostic studies involved organoleptic study, fluorescence analysis, preliminary photochemical studies and biochemical analysis. However, it is not a legal authority for statutory or regulatory purposes. Recent studies demonstrate coixol as a potent and nontoxic insulin secretagog from s. Scoparia dulcis licorice weed this plant can be weedy or invasive according to the authoritative sources noted below. Scoparia dulcis sdf7 endowed with glucose uptake properties on l6 myotubes compared insulin. Introduction increase risk of developing further resistant toward those as back old circumstances, in scanforsave for their illness, the general population searched themedications in nature. All plant leaves were evenly sprayed three times with 0. Scoparia dulcis has been popularly used to relieve discomfort caused by various painful conditions.
It is used in the treatment of respiratory and inflammatory diseases, diabetes, hype. The new structures were determined by various spectroscopic techniques, including 1 h nmr, c nmr, hmbc, hsqc, 1 h1 hcosy, roesy, and hresims. Coulibaly and others published protective effect of scoparia dulcis on brain and erythrocytes find, read and cite all the research you need on researchgate. The experiment was performed with wistar rats divided into 4 groups with 5 animals. Sad was administered orally at a dose of 10, 20 and 40 mg kg. Mar 31, 2006 we have investigated scoparia dulcis, an indigenous plant used in ayurvedic medicine in india, for its possible antihyperlipidemic effect in rats with streptozotocininduced experimental diabetes. Effect of the ethanolic extract of scoparia dulcis in. Pdf hispidulin and other constituents of scoparia dulcis linn. Two new labdane diterpenoids from scoparia dulcis to. Wed like to understand how you use our websites in order to improve them.
Aqueous extract of scoparia dulcis plant was administered orally 200 mgkg body weight and the effect of extract on blood glucose. Pdf cytokinin induced shoot regeneration and flowering. About the classification report about the classification download. Analgesic and antiinflammatory properties of scoparia dulcis. Phytoconstituents presenting in herbal plant broths are the biocompatible, regenerative, and costeffective sources that can be utilized for green synthesis of silver nanoparticles. Two new diterpenes, closely related to scopadulcic acids and scoparic acids, have been isolated from scoparia dulcis. Antisickling and toxicological evaluation of the leaves of scoparia dulcis linn scrophulariaceae. Antidiabetic and antioxidant effect of scoparia dulcisin. Scrophulariaceae, is a perennial herb which is commonly found in tropical and. The structure of a new diterpene was determined to be 6benzoyllabda817,diene15,18diol by spectroscopic methods.
Scoparia dulcis linn belongs to the family scrophulariaceae and have speculated medicinal properties. Acetylated flavonoid glycosides potentiating ngf action from. Scoparia dulcis in the germplasm resources information network grin, u. The website also provides access to a database and images of herbarium specimens found at the university of south florida and other herbaria. The antimicrobial activity of the plant were tested by broth. Chemical tests were employed in phytochemical investigations. Sensitive quantification of coixol, a potent insulin. Scoparia dulcis is an annual erect herb distributed throughout tropical and subtropical regions of india, america, brazil, west indies, and myanmar. Antidiabetic properties, bioactive constituents, and other. Scoparia grandiflora nash scoparia gypsophyloides walp. Scoparia dulcis is a species of flowering plant in the plantain family.
A downloadable pdf document of a book in prepublication awaiting illustration. Common names include licorice weed, goatweed, scopariaweed and sweetbroom in english, tapeicava, tapixaba, and vassourinha in portuguese, escobillo in spanish, and tipycha kuratu in guarani. Erect shrubby weed ft flowers white or bluish, usually 4 petals, densely bearded inside. Scopadulciol 1, a scopadulantype diterpenoid, was isolated from scoparia dulcis along with three other compounds 24 by an activityguided approach using the tcf reporter top luciferasebased assay system. The whole plant is used for ailments like diarrhea, stomachache, kidney stones, kidney problems, and fever. Phytochemical analysis and antibacterial activities of. Protective role of scoparia dulcis plant extract on brain.
Several unique diterpenes ex, scopadulcic acid b sdb and scopadulciol etc. Vijayakumari p lant kingdom is an everlasting reservoir of wonderful molecules with varying biological activities. Review article antidiabetic properties, bioactive constituents, and other therapeutic effects of scoparia dulcis geethipamunuwa, 1 d. Scoparia dulcis, a herbal product, is widely used for treatment of diabetes.
Antimicrobial screening of scoparia dulcis and eclipta. Nanomaterials free fulltext green silver nanoparticles. Cytokinin induced shoot regeneration and flowering of scoparia dulcis l. This is a small herb with very smallflowers of about 8 mm. Nephroprotective potential of plant was tested at two different doses in curative. Mahabbat e khoda3 1institute of biological sciences, 2department of genetic engineering. Scoparia dulcis linn contains flavonoids, tannins and saponins which have sedatif hypnotic effect. Pdf hispidulin and other constituents of scoparia dulcis. A new chemotype was found in scoparia dulcis from taiwan, china and thailand based on the diterpene composition. Wankupar wankhar, sakthivel srinivasan, ravindran rajan and. This study was aimed at investigating the antisickling activity of the leaves of the plant as well as establishing the toxicological profile. Classification for kingdom plantae down to species scoparia dulcis l. Scopadulciol, isolated from scoparia dulcis, induces.
Protective role of scoparia dulcis plant extract on brain antioxidant. Therapeutic use of scoparia dulcis reduces the progression of. Yield of methanol and aqueous extract of scoparia dulcis. Evaluation of the antisickling activity involved the inhibition of sodium.
An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region the fresh or dried plants are used externally to treat a wide range of skin problems, including pimples, impetigo, ulcers, eczema, bruises and contusions. Rumana hoque, deepali varshikar, akalpita tendulkar. Phytochemical investigation of the ethanol extract of the whole plant of scoparia dulcis, has resulted in the isolation of 4, 5, 7trihydroxy6methoxyflavone. On close observation the flowers appeared to be regular. Scoparia dulcis lady bird johnson wildflower center. Evaluation of antibacterial, antioxidant activity and. Antioxidant activity of water extract of scoparia dulcis sciencedirect. Scoparia dulcis linn scrophulariaceae together with other medicinal plants serve as antisickling remedies in africa. At the end of the experimental period, the sadtreated stz. Scoparia dulcis linn is a substantial ethnomedicinal plant which is commonly known as sweet broom weed is a perennial plant which is distributed widely in subtropical and tropical regions of india, brazil, america, myanmar and west indies. Pdf antisickling and toxicological evaluation of the.
Scoparia dulcis, eclipta alba, antimicrobial test, agar well diffusion, minimum inhibitory concentration mic 1. Elucidation of terpenoid metabolism in scoparia dulcis by rna. Scoparia dulcis, also known as sweet broomweed family. In this study significant free radical scavenging activity was determined by evaluating the inhibition concentration ic50 in each test. Medicinal plants and their derivatives represent a frequent alternative for the treatment of diseases 11. The structure and stereochemistry of the compounds were determined by spectroscopic. Media in category scoparia dulcis the following 75 files are in this category, out of 75 total.
This plant may be known by one or more common names in. The new chemotype was characterized by the presence of scopadulciol and scopadiol. Scrophulariaceae is reputed for its medicinal property. Effect of an aqueous extract of scoparia dulcis on blood glucose, plasma insulin and some polyol pathway enzymes in experimental rat diabetes. Diabetes mellitus is a metabolic disorder characterized by hyperglycemic, glucoseurea and negative nitrogen balance and it is mainly due to lack. No plant extract of scoparia dulcis weight of dry extracts in grams initial dry plant extracts in grams extraction yield % after freeze drying 1. Agronomy sellers, brent a pasture weeds scrophulariaceae taxonomic family goatweed biology and control in pastures 1. Abstractthe triterpenoids of scoparia dulcis were identified as friedelin, glutinol, aamyrin, betulinic acid, ifflaionic acid and dulcioic acid. Aqueous extract of scoparia dulcis plant was administered orally 200 mgkg body weight and the effect of extract on blood glucose, plasma insulin and the levels of thiobarbituric acid reactive substances tbars, hydroperoxides, superoxide dismutase sod, catalase cat, glutathione peroxidase gpx, glutathionestransferase gst and reduced glutathione gsh were. Analgesic and antiinflammatory properties of scoparia. A fluorometric microculture cytotoxicity assay fmca revealed that compound 1 was cytotoxic to ags human gastric adenocarcinoma cells. Antidiabetic and antioxidant activity of scoparia dulcis linn. Preliminary phytochemical analysis of different solvent.
A study was carried out at avinashilingam institute for home science and higher education for women coimbatore to evaluate the pharmacognostic, phytochemical and biochemical aspect of scoparia dulcis l. Agnps based on three kinds of leaf extracts phyllanthus urinaria, pouzolzia zeylanica, and scoparia dulcis, respectively and demonstrated the antifungal capacity. Scoparia dulcis is a rich source of flavones, terpenes and steroids2,3. The objective of the study is to evaluate the analgesic and antiinflammatory effect of the crude extract of s. Plantaginaceae is a perennial herb widely distributed in tropical areas. Elucidation of terpenoid metabolism in scoparia dulcis by. Diabetes is a major global health problem which requires new studies for its prevention and control. Scoparia dulcis sweet broom, licorice weed, vassourinha. In scoparia dulcis plant chloroform, ethyl acetate, acetone and methanol extract showed good zone of inhibition against b.
Phytochemicals screening and antimicrobial efficacy of scoparia. Scoparia dulcis linn scrophulariaceae against clinical isolates. International journal of scientific and research publications, volume 4, issue 12, december 2014 keywords. Antisickling and toxicological evaluation of the leaves of. From a distance i thought it to be a lamiaceae member.
Visited 362 times, 1 visits today downloads pdf downloads. We evaluated the antihyperglycaemic effect of scoparic acid d sad, a diterpenoid isolated from the ethanol extract of scoparia dulcis in streptozotocin stzinduced diabetic male wistar rats. Antihyperlipidemic effect of scoparia dulcis sweet broomweed. Scoparia dulcis iobserved this plant near paud in ghat section by the roadside. Philippine herbal medicines an illustrated compilation of philippine medicinal plants by dr godofredo stuart, with botanical information, chemical properties, folkloric uses and research studies. Pdf protective effect of scoparia dulcis on brain and. Antimicrobial screening of scoparia dulcis and eclipta alba plant extract. Pdf antioxidant study of different extracts of scoparia dulcis. Pdf phytochemical analysis and antimicrobial activity of scoparia. The aim of the study was to investigate the effect of aqueous extract of scoparia dulcis on the occurrence of oxidative stress in the brain of rats. Supplementary material for isolation and characterization of. The atlas of florida plants provides a source of information for the distribution of plants within the state and taxonomic information. Jul 01, 2004 scoparia dulcis plant extract is tried for prevention and treatment of diabetes mellitus induced experimentally by streptozotocin injection.
Uji efek hipnotiksedatif ekstrak etanol 70 % batang jaka. Antisickling and toxicological evaluation of the leaves of scoparia. Lady bird johnson wildflower center focused on protecting and preserving north americas native plants through native plant lists and image galleries, conservation, education, natural landscapes, seed collection millennium seed bank msb project, preserving and restoring native communities, spreading awareness on invasive species and gardening to attract wildlife. Different plant extracts can form nanoparticles with specific sizes, shapes, and properties. The hypnotic effect of 70% ethanolic extracts of scoparia dulcis linn stem on swiss webster malemice dyah ayu purwita sari, safari wahyu jatmiko medical faculty, muhammadiyah surakartauniversity background. Preliminary phytochemical analysis of different solvent extracts of scoparia dulcis l. Pdf two medicinal plants, scoparia dulcis scrophulariaceae and nymphaea lotus nympaeaceae were studied. Common names include licorice weed, goatweed, scoparia weed and sweetbroom in english, tapeicava, tapixaba, and vassourinha in portuguese, escobillo in spanish, and tipycha kuratu in guarani.
Antihyperglycaemic effects of herbal porridge made of. The aim of the study was to investigate the effect of aqueous extract of scoparia dulcis on the occurrence of oxidative stress in the brain of rats during diabetes by measuring the extent of oxidative damage as well as the status of the antioxidant defense system. Antimicrobial screening of scoparia dulcis and eclipta alba. To evaluate the nephroprotective potential of ethanolic extract of aerial parts of plant scoparia dulcis against cisplatin induced nephrotoxicity in wistar rats. While every effort has been made to provide the most reliable and uptodate information available, ultimate legal requirements with respect to species are contained in. Free radical scavenging activity was observed in both the methanol extract m. A single dose of streptozotocin 45 mgkg body weight produced decrease in insulin, hyperglycemia, increased lipid peroxidation thiobarbituric reactive substances and lipid hydroperoxides and decreased. Improved plastid transformation efficiency in scoparia dulcis l. The analgesic, antiinflammatory and antipyretic activities of the water we and ethanolic ee extracts of scoparia dulcis l. During the field exploration from chandrapur district an interesting plant of family plantaginaceae collected from vidharbha region of maharashtra state. Many higher plants accumulate extractable organic substances in quantities sufficient to be economically useful as chemical. Scoparia dulcis is a rich source of flavones, terpenes and steroids2,3 after the recommendations made by world health organization.568 414 299 331 1446 1455 427 511 1228 1568 711 965 720 1041 1437 341 214 174 830 1462 1181 931 770 1178 529 819 1582 952 933 1457 571 1383 675 1152 649 994 1492 623 710